Neurobiology of Disease Subthalamic Nucleus Neurons Are Synchronized to Primary Motor Cortex Local Field Potentials in Parkinson’s Disease
نویسندگان
چکیده
Shoichi A. Shimamoto,1* Elena S. Ryapolova-Webb,1* Jill L. Ostrem,2 Nicholas B. Galifianakis,2,3 Kai J. Miller,4 and Philip A. Starr1,3 Departments of 1Neurological Surgery and 2Neurology, University of California, San Francisco, California 94143, and 3Parkinson’s Disease Research, Education, and Care Center, San Francisco Veteran’s Affairs Medical Center, San Francisco, California 94143-0114, and 4Department of Neurosurgery, Stanford University, Stanford, California 94305
منابع مشابه
Suppression of beta oscillations in the subthalamic nucleus following cortical stimulation in humans
It is unclear how subthalamic nucleus activity is modulated by the cerebral cortex. Here we investigate the effect of transcranial magnetic stimulation (TMS) of the cortex on oscillatory subthalamic local field potential activity in the 8-35 Hz (alpha/beta) band, as exaggerated synchronization in this band is implicated in the pathophysiology of parkinsonism. We studied nine patients with Parki...
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تاریخ انتشار 2013